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However, in any given case, the amount of compound administered will depend on such factors as the solubility of the active component, the formulation used and the route of administration. A prodrug is a compound that is transformed in vivo to yield a compound of the present invention, . The transformation may occur by various mechanisms, such as through hydrolysis in blood. A good discussion of the use of prodrugs is provided by T. Stella, «Pro-drugs as Novel Delivery Systems,» Vol.

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